The Global Paroxysmal Nocturnal Hemoglobinuria Therapeutics Market size is forecast to grow from USD 1.4 Billion in 2025 to approximately USD 4.2 Billion by 2035. According to Decision Advisors, a detailed research report on the paroxysmal nocturnal hemoglobinuria therapeutics market indicates that the rapid expansion of the complement inhibitor therapies trend dominates the market, accounting for approximately 60-63% of the total share globally. Alexion Pharmaceuticals (AstraZeneca) leads the market with an estimated 35-40% global market share. The company reported a 2025 revenue of approximately USD 45+ Billion, making it one of the most influential forces shaping industry trends and overall market growth