Hydrocortisone injection in limited supply – DHSC alerts pharmacists

Pharmacists are being notified of a limited supply of hydrocortisone sodium phosphate 100mg/1ml solution for injection ampoules, with stock expected to be exhausted by late March 2025. The Department of Health and Social Care (DHSC) has issued a medicine supply notification, indicating that resupply is not anticipated until May 2026. NHS provider Trust pharmacy procurement and clinical teams are advised to collaborate in reserving existing stock of the solution for injection, specifically for patients who require hydrocortisone sodium phosphate during an adrenal crisis. The DHSC added that this stock has an expiry date of June 2025. Hydrocortisone is used to replace steroids in individuals with adrenal insufficiency, such as those with Congenital Adrenal Hyperplasia (CAH) or Addison’s disease, where the adrenal glands produce insufficient natural steroids. People with adrenal insufficiency or anyone who is “steroid-dependent” require a hydrocortisone emergency injection kit to prevent an acute adrenal crisis, which can be life-threatening.