Preventing bedsores in bedridden patients starts with one simple rule — never let skin stay under pressure for more than two hours. When the body stays in one position too long, blood flow stops reaching the skin over bony areas. The tissue breaks down quickly without oxygen and nutrients. Changing the patient\'s position every two hours during the day is the most effective bedsore prevention step any caregiver can take. Use soft pillows to support new positions and keep bony areas off the mattress. Combined with daily skin checks and Cimidaxil D+ wound healing spray applied to vulnerable pressure areas, this repositioning routine gives bedridden patients strong, consistent protection against pressure sore development throughout the day and night.