Microbiome skincare products are substances incorporated in biologic drugs with active pharmaceutical ingredients (APIs) for the stability, safety, bioavailability, and good efficacy without therapeutic benefits. Excipients act as protectants and play an important role in the stability of sensitive biologics such as antibodies, vaccines, proteins, and other biological products by countering detrimental physical, chemical, or biological conditions that lead to degradation of biologic drugs, such as temperature, light, pH, and agitation.